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NAD+

500mg
$55.00
NAD+ 500mg product photograph
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Nicotinamide Adenine Dinucleotide. Foundational coenzyme referenced across published literature investigating mitochondrial bioenergetics, sirtuin-pathway biology, and cellular redox mechanisms.

  • Mitochondrial biology research
  • Cellular bioenergetics
  • Cold-chain handled, third-party tested
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Independent lab verification · current batch
  • THIRD-PARTY TESTED
  • COLD-CHAIN HANDLED
  • TRACKED SHIPPING
  • QUALITY-FOCUSED SOURCING
SPECIFICATIONS
Product
NAD+
Strength
500mg
Vial Size
500mg per vial
SKU
VLR-NAD-500
Batch / Lot
Current batch listed on COA
Storage
Refrigerate 2–8°C · protect from light
Form
Lyophilized powder
RESEARCH USE ONLY

Sold strictly for laboratory and research purposes — never for human consumption, food, drug, or cosmetic use. 21+ only. A standard we hold ourselves to, not just the law.

EDUCATIONAL OVERVIEW

About this compound

Context, not noise — what the research actually says.

WHAT IT IS

A research compound investigated in mitochondrial biology and cellular bioenergetics literature.

RECOVERY
KEY BENEFITS
  • Studied in cellular bioenergetic pathways
  • Investigated in oxidative-balance literature
  • Referenced in sirtuin and cellular-signaling research
COMMON USES
  • Mitochondrial biology research
  • Cellular bioenergetics studies
  • Foundational layer across the catalog
THINGS TO KNOW
  • Lyophilized — requires reconstitution with BAC water
  • Refrigerate; protect from light
  • Research use only — not for human consumption
RELATED COLLECTION
Cellular Recovery Research Collection

Pairs with MOTS-c + SS-31 — A three-vial collection assembled around mitochondrial biology and cellular bioenergetics research.

VIEW COLLECTION
COLLECTION PRICE
$130.00
STORAGE

Cold-chain handling

REFRIGERATED
Store unopened at 36–46°F (2–8°C).
RECONSTITUTED
Keep refrigerated. Do not freeze.
PROTECT FROM LIGHT
Original packaging until use.

Store unopened vials refrigerated at 36–46°F (2–8°C). After reconstitution, keep refrigerated and use within the timeframe specified by your laboratory practice. Protect from light. Do not freeze reconstituted solution.

SHIPPING

Shipping information

Insulated, tracked, and handled with care from our facility to yours.

PROCESSING
Ships within 48 hours of order confirmation.
COLD-CHAIN
Insulated packaging with ice packs for temperature-sensitive compounds.
TRACKED & INSURED
Tracking provided. Domestic delivery typically 2–5 business days.

Local pickup is available by appointment for customers in the Phoenix, Arizona area. See the full shipping policy for details, accepted payment methods, and scheduling.

FAQ

Common questions

SCIENTIFIC RESEARCH OVERVIEW · SRO

Scientific Research Overview

A structured summary of published scientific literature on this compound — provided for educational reference only.

Cellular Health Research
RESEARCH SNAPSHOT
Research Category
Investigational cellular redox coenzyme and signaling metabolite
Biological Targets
  • NAD+ metabolism
  • Sirtuins
  • PARP enzymes
  • Mitochondrial energy pathways
Primary Areas of Research
Mitochondrial bioenergetics · Cellular redox balance · Sirtuin pathway signaling · PARP-mediated DNA repair · NAD+ biosynthesis and salvage pathways · Age-related metabolic decline
Current Stage of Research
Preclinical and Human Clinical Research
WHAT IS NAD+ (NICOTINAMIDE ADENINE DINUCLEOTIDE)?

Nicotinamide adenine dinucleotide (NAD+) is a ubiquitous coenzyme and signaling metabolite investigated across the scientific literature for its central roles in cellular redox reactions, mitochondrial energy metabolism, and post-translational enzyme regulation. It exists in oxidized (NAD+) and reduced (NADH) forms and serves as an essential cofactor for sirtuins, poly(ADP-ribose) polymerases (PARPs), and other NAD+-consuming enzymes. Research spans preclinical models and human clinical trials of NAD+ precursors such as nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN).

PRIMARY AREAS OF RESEARCH
  • Mitochondrial bioenergetics
  • Cellular redox balance
  • Sirtuin pathway signaling
  • PARP-mediated DNA repair
  • NAD+ biosynthesis and salvage pathways
  • Age-related metabolic decline

  • Published studies have investigated NAD+ as a cofactor for sirtuins, PARPs, and CD38 in cellular and animal models.
  • Research suggests age-related decline in tissue NAD+ concentrations across multiple species and human cohorts.
  • Current evidence indicates that NAD+ precursors such as NR and NMN can raise NAD+ levels and influence markers of mitochondrial function, oxidative stress, and metabolic health in preclinical and clinical studies.
  • Investigators have observed effects on cardiovascular, skeletal-muscle, and neurodegenerative-disease models in published preclinical datasets, with early human trials examining safety, tolerability, and biomarker outcomes.

NAD+ is being studied as a central mediator of energy metabolism and cellular signaling. Current evidence indicates that NAD+ participates in redox cycling (NAD+/NADH) within glycolysis, the tricarboxylic-acid cycle, and oxidative phosphorylation. It also serves as a substrate for sirtuin-mediated deacetylation, PARP-driven DNA repair, and CD38/NADase activity. Published work suggests that NAD+ availability influences mitochondrial function, oxidative stress responses, and the activity of nutrient-sensing pathways associated with longevity and metabolic health.
CURRENT AREAS OF INVESTIGATION
  • Mitochondrial Function
  • Cellular Repair
  • Healthy Aging
  • Metabolic Health
  • Redox Biology
  • Energy Metabolism

  1. Imai S, Guarente L. NAD+ and sirtuins in aging and disease. Trends Cell Biol. 2014;24(8):464-471. View source
  2. Yoshino J, Baur JA, Imai SI. NAD+ intermediates: the biology and therapeutic potential of NMN and NR. Cell Metab. 2018;27(3):513-528. View source
  3. Mills KF, Yoshida S, Stein LR, et al. Long-term administration of nicotinamide mononucleotide mitigates age-associated physiological decline in mice. Cell Metab. 2016;24(6):795-806. View source
  4. Rajman L, Chwalek K, Sinclair DA. The therapeutic potential of NAD+ boosting molecules: the in vivo evidence. Cell Metab. 2018;27(3):529-547. View source
  5. Covarrubias AJ, Perrone R, Grozio A, Verdin E. NAD+ metabolism and its roles in cellular processes during ageing. Nat Rev Mol Cell Biol. 2021;22(2):119-141. View source
RESEARCH STATUS

This compound continues to be investigated in preclinical and/or clinical research. Scientific understanding continues to evolve as additional studies are published.

RESEARCH DISCLAIMER

For laboratory research use only. This information summarizes published scientific literature for educational purposes only and is not intended to diagnose, treat, cure, or prevent any disease.

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RESEARCH DISCLAIMER

All VELOR compounds are sold strictly for laboratory and research purposes only. They are not intended for human consumption, ingestion, or any food, drug, cosmetic, or therapeutic use. By purchasing, you confirm you are 21+ and a qualified researcher or research institution. Statements have not been evaluated by the FDA.

RECOVERY
NAD+
$55.00
1